Renin

A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.

Also Known As:

Big Renin; Cryorenin; Inactive Renin; Pre-Prorenin; Preprorenin; Prorenin; Angiotensin Forming Enzyme; Pre Prorenin; Renin, Big; Renin, Inactive; Angiotensin-Forming Enzyme; Angiotensinogenase

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Peptide Hydrolases: 24289
      - Endopeptidases: 643
        Aspartic Acid Endopeptidases: 2
        Renin: 12649
      - Proprotein Convertases: 512
        Renin: 12649
      - Aspartic Acid Proteases: 414
        Aspartic Acid Endopeptidases: 2
        Renin: 12649

H Brenneis Selected Research

H Brenneis Research Topics

Disease

Drug/Important Bio-Agent (IBA)